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1992 1
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Page 1
36th International Symposium on Intensive Care and Emergency Medicine : Brussels, Belgium. 15-18 March 2016.
Bateman RM, Sharpe MD, Jagger JE, Ellis CG, Solé-Violán J, López-Rodríguez M, Herrera-Ramos E, Ruíz-Hernández J, Borderías L, Horcajada J, González-Quevedo N, Rajas O, Briones M, Rodríguez de Castro F, Rodríguez Gallego C, Esen F, Orhun G, Ergin Ozcan P, Senturk E, Ugur Yilmaz C, Orhan N, Arican N, Kaya M, Kucukerden M, Giris M, Akcan U, Bilgic Gazioglu S, Tuzun E, Riff R, Naamani O, Douvdevani A, Takegawa R, Yoshida H, Hirose T, Yamamoto N, Hagiya H, Ojima M, Akeda Y, Tasaki O, Tomono K, Shimazu T, Ono S, Kubo T, Suda S, Ueno T, Ikeda T, Hirose T, Ogura H, Takahashi H, Ojima M, Kang J, Nakamura Y, Kojima T, Shimazu T, Ikeda T, Suda S, Izutani Y, Ueno T, Ono S, Taniguchi T, O M, Dinter C, Lotz J, Eilers B, Wissmann C, Lott R, Meili MM, Schuetz PS, Hawa H, Sharshir M, Aburageila M, Salahuddin N, Chantziara V, Georgiou S, Tsimogianni A, Alexandropoulos P, Vassi A, Lagiou F, Valta M, Micha G, Chinou E, Michaloudis G, Kodaira A, Ikeda T, Ono S, Ueno T, Suda S, Izutani Y, Imaizumi H, De la Torre-Prados MV, Garcia-De la Torre A, Enguix-Armada A, Puerto-Morlan A, Perez-Valero V, Garcia-Alcantara A, Bolton N, Dudziak J, Bonney S, Tridente A, Nee P, Nicolaes G, Wiewel M, Schultz M, Wildhag… See abstract for full author list ➔ Bateman RM, et al. Crit Care. 2016 Apr 20;20(Suppl 2):94. doi: 10.1186/s13054-016-1208-6. Crit Care. 2016. PMID: 27885969 Free PMC article.
Diedrich P242 - A reduction in tidal volumes for ventilated patients on ICU calculated from IBW. can it minimise mortality in comparison to traditional strategies? A . Fuller, P. McLindon, K. Sim P243 - Predictive value of lung aeration scoring using lung ultrasound …
Diedrich P242 - A reduction in tidal volumes for ventilated patients on ICU calculated from IBW. can it minimise mortality in comparison to …
HIF-1alpha switches the functionality of TGF-beta signaling via changing the partners of smads to drive glucose metabolic reprogramming in non-small cell lung cancer.
Huang Y, Chen Z, Lu T, Bi G, Li M, Liang J, Hu Z, Zheng Y, Yin J, Xi J, Lin Z, Zhan C, Jiang W, Wang Q, Tan L. Huang Y, et al. J Exp Clin Cancer Res. 2021 Dec 20;40(1):398. doi: 10.1186/s13046-021-02188-y. J Exp Clin Cancer Res. 2021. PMID: 34930376 Free PMC article.
We found that transforming growth factor (TGF)-beta plays a dual function in regulating glycolysis and cell proliferation in non-small cell lung cancer. METHODS: We used the PET/MRI imaging system to observe the glucose metabolism of subcutaneous tumors in nude mice. Energ …
We found that transforming growth factor (TGF)-beta plays a dual function in regulating glycolysis and cell proliferation in non-small cell …
Differential expression of Rb2/p130 and p107 in normal human tissues and in primary lung cancer.
Baldi A, Esposito V, De Luca A, Fu Y, Meoli I, Giordano GG, Caputi M, Baldi F, Giordano A. Baldi A, et al. Clin Cancer Res. 1997 Oct;3(10):1691-7. Clin Cancer Res. 1997. PMID: 9815552
Terminally differentiated cells, such as neurons and skeletal muscle, showed high expression levels for Rb2/p130, whereas p107 was expressed at higher levels in other cell types such as epithelia of the breast and prostate. We then examined the expression pattern of Rb2/p1 …
Terminally differentiated cells, such as neurons and skeletal muscle, showed high expression levels for Rb2/p130, whereas p107 was ex …
Differential expression of the retinoblastoma gene family members pRb/p105, p107, and pRb2/p130 in lung cancer.
Baldi A, Esposito V, De Luca A, Howard CM, Mazzarella G, Baldi F, Caputi M, Giordano A. Baldi A, et al. Clin Cancer Res. 1996 Jul;2(7):1239-45. Clin Cancer Res. 1996. PMID: 9816293
The Rb (retinoblastoma) gene family is composed of three members: the RB gene (one of the best-studied tumor suppressor genes) and two related genes, p107 and pRb2/p130. These three proteins share many structural and functional features and play a fundamental role in growt …
The Rb (retinoblastoma) gene family is composed of three members: the RB gene (one of the best-studied tumor suppressor genes) and two relat …
CRISPR-mediated modeling and functional validation of candidate tumor suppressor genes in small cell lung cancer.
Ng SR, Rideout WM 3rd, Akama-Garren EH, Bhutkar A, Mercer KL, Schenkel JM, Bronson RT, Jacks T. Ng SR, et al. Proc Natl Acad Sci U S A. 2020 Jan 7;117(1):513-521. doi: 10.1073/pnas.1821893117. Epub 2019 Dec 23. Proc Natl Acad Sci U S A. 2020. PMID: 31871154 Free PMC article.
Small cell lung cancer (SCLC) is a highly aggressive subtype of lung cancer that remains among the most lethal of solid tumor malignancies. ...In addition, we observe differences in proliferation and apoptosis as well as altered distribution of initiated tumors in t …
Small cell lung cancer (SCLC) is a highly aggressive subtype of lung cancer that remains among the most lethal of solid tumor …
RBL1 (p107) functions as tumor suppressor in glioblastoma and small-cell pancreatic neuroendocrine carcinoma in Xenopus tropicalis.
Naert T, Dimitrakopoulou D, Tulkens D, Demuynck S, Carron M, Noelanders R, Eeckhout L, Van Isterdael G, Deforce D, Vanhove C, Van Dorpe J, Creytens D, Vleminckx K. Naert T, et al. Oncogene. 2020 Mar;39(13):2692-2706. doi: 10.1038/s41388-020-1173-z. Epub 2020 Jan 30. Oncogene. 2020. PMID: 32001819
Alterations of the retinoblastoma and/or the p53 signaling network are associated with specific cancers such as high-grade astrocytoma/glioblastoma, small-cell lung cancer (SCLC), choroid plexus tumors, and small-cell pancreatic neuroendocrine carcinoma (SC-PaNEC). However …
Alterations of the retinoblastoma and/or the p53 signaling network are associated with specific cancers such as high-grade astrocytoma/gliob …
RBL2/p130 is a direct AKT target and is required to induce apoptosis upon AKT inhibition in lung cancer and mesothelioma cell lines.
Pentimalli F, Forte IM, Esposito L, Indovina P, Iannuzzi CA, Alfano L, Costa C, Barone D, Rocco G, Giordano A. Pentimalli F, et al. Oncogene. 2018 Jul;37(27):3657-3671. doi: 10.1038/s41388-018-0214-3. Epub 2018 Apr 2. Oncogene. 2018. PMID: 29606701
The retinoblastoma (RB) protein family includes RB1/p105, RBL1/p107, and RBL2/p130, which are key factors in cell-cycle regulation and stand at the crossroads of multiple pathways dictating cell fate decisions. ...We found that pharmacological inhibition of AKT, through th …
The retinoblastoma (RB) protein family includes RB1/p105, RBL1/p107, and RBL2/p130, which are key factors in cell-cycle regulation an …
Role of the Holoenzyme PP1-SPN in the Dephosphorylation of the RB Family of Tumor Suppressors During Cell Cycle.
Verdugo-Sivianes EM, Carnero A. Verdugo-Sivianes EM, et al. Cancers (Basel). 2021 May 6;13(9):2226. doi: 10.3390/cancers13092226. Cancers (Basel). 2021. PMID: 34066428 Free PMC article. Review.
Cell cycle progression is highly regulated by modulating the phosphorylation status of the retinoblastoma protein (pRB) and the other two members of the RB family, p107 and p130. This process is controlled by a balance in the action of kinases, such as the complexes formed …
Cell cycle progression is highly regulated by modulating the phosphorylation status of the retinoblastoma protein (pRB) and the other two me …
The human cytomegalovirus IE1-72 protein interacts with the cellular p107 protein and relieves p107-mediated transcriptional repression of an E2F-responsive promoter.
Poma EE, Kowalik TF, Zhu L, Sinclair JH, Huang ES. Poma EE, et al. J Virol. 1996 Nov;70(11):7867-77. doi: 10.1128/JVI.70.11.7867-7877.1996. J Virol. 1996. PMID: 8892909 Free PMC article.
Expression patterns of p107 protein levels during HCMV infection of human embryonic lung cells (HELs) demonstrate a sustained induction from early to late times of infection. ...Our data demonstrate that the interaction between p107 and the IE1-72 protein occ …
Expression patterns of p107 protein levels during HCMV infection of human embryonic lung cells (HELs) demonstrate a sustained …
Protein expression of the RB-related gene family and SV40 large T antigen in mesothelioma and lung cancer.
Modi S, Kubo A, Oie H, Coxon AB, Rehmatulla A, Kaye FJ. Modi S, et al. Oncogene. 2000 Sep 21;19(40):4632-9. doi: 10.1038/sj.onc.1203815. Oncogene. 2000. PMID: 11030152
Mutational inactivation of the RB-related gene RBL2/p130 has been reported as a common and important prognostic factor in human lung cancer. To examine the role of the RB-related gene family in lung cancer we analysed the protein expression of the RB gene in cell li …
Mutational inactivation of the RB-related gene RBL2/p130 has been reported as a common and important prognostic factor in human lung …
44 results